- Thursday, July 18, 1991
- The Synthesis of Substituted Benzothieno[2,3-c]quinolines and their N-methyl Quaternary Salts
- Published at:Not Found
Four substituted benzothietto[2,3-c]quinolines 14a-14d were prepared by photocyclization of the appropriate carboxamides 8a-8d to the corresponding benzothieno[2,3-c]quinolin-6(5H)-ones 12a-12d followed by chlorination to 6-c:hlorobenzothieno[2,3-c]quittolines 13a-13d and dechlorination resulting in the title compounds. Treatment of 14a-14d with iodomethane furnished the corresponding N-methyl quaternary salts 5a-5d.