An-Najah National University

Head of Department


  • Wednesday, January 28, 2009
  • Biological effects of 6 mT static magnetic fields: a comparative study in different cell types.
  • Published at:Not Found
  • Tenuzzo B, Chionna A, Panzarini E, Lanubile R, Tarantino P, Di Jeso B, Dwikat M, Dini L.
    Department of Biological and Environmental Science and Technology, University of Lecce, Lecce, Italy.
    The present work was a comparative study of the bio-effects induced by exposure to 6 mT static magnetic field (MF) on several primary cultures and cell lines. Particular attention was dedicated to apoptosis. Cell viability, proliferation, intracellular Ca(2+) concentration and morphology were also examined. Primary cultures of human lymphocytes, mice thymocytes and cultures of 3DO, U937, HeLa, HepG2 and FRTL-5 cells were grown in the presence of 6 mT static MF and different apoptosis-inducing agents (cycloheximide, H(2)O(2), puromycin, heat shock, etoposide). Biological effects of static MF exposure were found in all the different cells examined. They were cell type-dependent but apoptotic inducer-independent. A common effect of the exposure to static MF was the pr
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  • Tuesday, January 27, 2009
  • Static magnetic field selects undifferentiated myelomonocytes from low-glutamine concentration stimulated U937 cells.
  • Published at:Not Found
  • Tenuzzo B, Dwikat M, Dini L.
    Department of Biological and Environmental Science and Technology, University of the Salento, Via per Monteroni, 73100 Lecce, Italy.
    Reduced glutamine (GLN) concentration in the culture medium of a U937 cell line caused them to be differentiated along the monocytic pathway; cells attached to the matrix and to each other by extending pseudopodia and acquired specific functional characteristics, such as the expression of alpha-naphthyl-acetate esterase and the capacity to reduce nitroblue tetrazolium, as well as becoming active phagocytes. When U937 cells were differentiated under continuous exposure to a 6mT static magnetic field (MF) the overall differentiation process was perturbed. Surprisingly, after 5 days' exposure to the static MF, higher cell viability and differentiation were observed in cells cultured in a GLN-deprived medium than in cells grown in the same medium but in the absence of a static MF. The latter cells, particularly those that we
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Majdi Bahjat Mohammad Dwikat
Biotechnology-Human Physiology
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