An-Najah National University

Publications of Waleed M. Sweileh,

Research Interests: 1.Clinical Renal Pharmacology and Therapeutics 2.Evidence Based Pharmacotherapy 3.Pharmacoepidemiology

 
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  • Friday, January 31, 2003
  • Effect of “Polypharmacy” and “Frequency of Drug Dosing” on Rate of Compliance among Diabetic and Hypertensive Patients: A Survey Study in Palestine
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    Effect of “Polypharmacy” and “Frequency of Drug Dosing” on Rate of

    Compliance among Diabetic and Hypertensive Patients: A Survey Study in Palestine

     

    Waleed Sweileh

    The objective of this study was to investigate the influence of polypharmacy and

    frequency of drug dosing on the rate of compliance among hypertensive and diabetic

    patients in the Palestinian community. The rate of compliance of 321 hypertensive and

    diabetic patients was assessed using graded questionnaire. The overall rate of

    compliance for the tested sample was 42.1%. Both, diabetic and hypertensive patients

    tend to have better compliance and less noncompliance when the number of

    medications is decreased. The best rate of compliance in both cases was obtained when

    patients have simple one drug regimen. Both, diabetic and hypertensive patients tend to

    have better compliance on once daily dosing (ODD) versus multiple daily dosing

    (MDD). However, diabetic but not hypertensive patients tend to have better compliance

    on once daily dosing versus twice daily dosing. These results indicate that although

    once daily dosing is associated with higher compliance but it is not always the best

    especially in treatment of hypertension as the treatment of some type of hypertension

    requirs more than one drug more daily doses, depends on the type of hypertension, as

    well as dirbetic melitiies. These results should encourage physicians in the hypertension

    and diabetes mellitus clinics of the Palestinian Ministry of Health (MOH) to minimize

    the number of prescribed medications to improve compliance, therapeutic outcome and

    to minimize cost.

    Abstract

    *, Ola Aker**, Saeed Hamooz**

     
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Waleed M. Sweileh, Professor of Clinical Pharmacology & Pharmacy:
 
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