- Saturday, January 1, 2005
- Post infection Purpura Fulminans in a patient heterozygous for Factor V Leiden and transient protein S deficiency
- Published at:Not Found
Purpura fulminans usually consists of large, often symmetrical, spreading ecchymosis, which may later develop into extensive areas of skin necrosis and peripheral gangrene as well as intra abdominal thrombosis. Postinfectious purpura fulminans has been described in a few cases. The interaction and the contribution of the mutations such as factor V Leiden and prothrombin G20210A to the development and progression of postinfectious purpura fulminans and venous thrombosis is a rare occurrence. We describe a patient heterozygous for factor V Leiden mutation who developed purpura fulminans secondary to acquired protein S deficiency associated with recent varicella infection.
An-Najah University Journal for Research - Natural Sciences (A) ISSN: 1727-2114
Volume 19 , 2005, Pages: 209-216