An-Najah Blogs :: Riad Ahmad Mohammad Najib Amer An-Najah Blogs :: Riad Ahmad Mohammad Najib Amer en-us Sun, 25 Oct 2020 04:04:30 IST Sun, 25 Oct 2020 04:04:30 IST Post infection Purpura Fulminans in a patient heterozygous for Factor V Leiden and transient protein S deficiency ArticlesPurpura fulminans usually consists of large often symmetrical spreading ecchymosis which may later develop into extensive areas of skin necrosis and peripheral gangrene as well as intra abdominal thrombosis Postinfectious purpura fulminans has been described in a few cases The interaction and the contribution of the mutations such as factor V Leiden and prothrombin G20210A to the development and progression of postinfectious purpura fulminans and venous thrombosis is a rare occurrence We describe a patient heterozygous for factor V Leiden mutation who developed purpura fulminans secondary to acquired protein S deficiency associated with recent varicella infection An-Najah University Journal for Research - Natural Sciences A ISSN: 1727-2114 Volume 19 2005 Pages: 209-216