The objective of this study was to determine the percentage of diabetics with hypertension who are using aspirin, and to report on any differences between males and females and age groups. Medical records of the 342 diabetic hypertensive patients were analyzed. The mean age of the patients in the sample was 64.4 years and male: female ratio was 1.03 : 1. Among the sample population studied, only 108/342 (31.5%) were using aspirin. Gender differences in aspirin therapy was noticed. Aspirin was used in 42/168 (25%) females versus 66/174 (38%) males. No significant age differences were seen in aspirin therapy. As a conclusion, aspirin use is low in diabetics with hypertension. Physicians in Palestine should be encouraged to use aspirin more in diabetics for both primary and secondary prevention of cardiovascular disease.