An-Najah National University

Bassam Ali Abu-Shanab


  • Sunday, June 1, 2008
  • Enterotoxigenecity of S. Aureus Isolates Recovered from Chronic Urogenital Tract Infection in North Palestine
  • Published at:Pak J Med Sci 2008 Vol. 24 No. 2
  • Objectives: Staphylococcus aureus is an important pathogen associated with diseases in a variety of hosts including humans. It produces several toxins and virulence factors that contribute to its pathogenic potential such as staphylococcal enterotoxins (SEs). This study was conducted to determine enterotoxigenicity of S. aureus associated with chronic urogenital tract infection by detecting enterotoxin genes.
    Setting: This study was done in The Microbiology laboratory, An-Najah N. University, Palestine.
    Methodology: A total of 90 S. aureus isolates recovered from clinical samples from patients suffering from chronic urogenital tract infection in the North of Palestine were used to detect the presence of staphylococcal enterotoxin genes sea, seb, sec, sed and see by polymerase chain reaction (PCR) assay.
    Results: Out of 90 S. aureus isolates tested, it was found that 57 (63.3%) of these isolates harboured one or more enterotoxin genes. Up to 78.9% of the enterotoxigenic isolates possessed
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  • Tuesday, January 1, 2008
  • In Vitro Activity of Certain Drugs in Combination with Plant Extracts against Staphylococcus Aureus Infections
  • Published at:Not Found
  • Objectives: This study has been done to evaluate the interaction between ethanolic extracts of Rhus coriaria (seed), Psidium guajava (Leaf), Lawsonia inermis (Leaf) and Sacropoterium spinosum (seed) and antimicrobial drugs including oxytetracycline HCl, enrofloxacin, gentamicin sulphate and sulfadimethoxine against four clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA).
    Methodology: Evaluation of the interaction between ethanolic extracts and different antimicrobial agents has been done using well-diffusion method.
    Results: It showed that ethanolic extracts increase the inhibition zones of oxytetracycline HCl, gentamicin sulphate, and sulfadimethoxine, while combinations between these plant extracts and enrofloxacin decrease inhibition zone.
    Conclusion: This study probably suggests the possibility of concurrent use of these antimicrobial drugs and plant extracts in combination in treating infections caused by S. aureus strains or at least the concomitant administrati
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  • Tuesday, January 1, 2008
  • Efficacy of Aqueous and Ethanol Extracts of Some Palestinian Medicinal Plants for Potential Antibacterial Activity
  • Published at:Not Found
  • Nine medicinal plants growing in Palestine were screened in vitro for potential antibacterial activity against 6 bacterial strains by well diffusion and micro-dilution techniques. Both aqueous and organic solvents were used. The dried extracts of Sacropoterium spinosum (Rosaceae) (seed), Ruta chalepensis L (Rutaceae) (leaf), Cassia senna (Ligumenosa) (leaf), Lawsonia inermis (Lythraceae) (leaf), Psidium guajava (Myrtaceae) (Leaf), Carataegus azerullus (Rosaceae) (Leaf), Ranunclus asiaticus(Ranunculaceae) (Flowers), Calendula officinalis (Composita) (Flowers),and Salvia syriaca (Labiatae) (leaf) were screened. The bacterial strains tested were; Methicillin-resistant Staphylococcus aureus (MRSA); three strains (1, 2 & 3), multidrug resistant Pseudomonas aeruginosa, Proteus vulgaris and Klebsiella pneumonia. The average diameter of inhibition zones ranged from 9 to 30 mm and 11 to 28 mm for aqueous and ethanol extract, respectively. Methicillin-resistant Staphylococcus aureus (MRSA) was the most inhibited mi
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  • Sunday, January 1, 2006
  • Antibacterial Activity of Four Plant Extracts Used in Palestine in Folkloric Medicine against Methicillin-Resistant Staphylococcus aureus
  • Published at:Not Found
  • Ethanolic and hot water extracts from 4 different plant species used in Palestine in popular medicine for the treatment of several ailments of microbial and non-microbial origin were evaluated for potential antimicrobial activity against methicillinresistant Staphylococcus aureus (MRSA). Both water and ethanol extracts of Mentha longifolia, Melissa officinalis and Rosa damascena were effective on MRSA. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of the ethanolic extract of M. longifolia and M. officinalis were in the range of 3.125 to 12.50 mg/ml and 12.50 to 25.00 mg/ml, respectively. The ethanolic extract with the greatest antimicrobial activity was that of R. damascena (MIC 0.395 to 0.780 mg/ml and MBC 1.563 to 3.125 mg/ml). The combination of ethanolic extracts of the plants studied showed synergistic antibacterial activity against MRSA strains.
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Bassam Ali Abdul Raheem Abu-Shanab
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