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- Thursday, May 28, 2009
- HIV-1 co-receptor CCR5 and CCR2 mutations among Greeks
- Published at:FEMS Immunology and Medical Microbiology 28 (2000) 87-89; Anna Papa, Evagelia Papadimitriou, Ghaleb Adwan, Jonathan P. Clewley, Nikos Malissiovas, Ioannis Ntoutsos, Stella Alexiou, Antonis Antoniadis
Abstract
The frequency of CCR5 and CCR2 alleles in human immunodeficiency virus (HIV)-positive and HIV-negative populations of Northern Greece was investigated. The frequency of the CCR5v32 allele among the HIV-negative subjects was 0.052, while it was approximately twofold lower among the seropositives, suggesting that the heterozygous genotype confers a partial resistance to the HIV infection. No significant difference in CCR2 allele frequency between the two groups was observed. Federation of European Microbiological-