An-Najah National University

Ghaleb Mohammad Adwan


  • Friday, November 23, 2012
  • Three new species of cercariae from Melanopsis praemorsa (L. 1758, Buccinum) snails in Al-Bathan fresh water body, Palestine
  • Published at:Asian Pacific Journal of Tropical Biomedicine (2012)S1064-S1069, Sami Bdir, Ghaleb Adwan
  • Objective: To investigate other new species of cercariae encountered in Melanopsis praemorsa (M. praemorsa) snails collected from Palestine. Methods: A total of 1 100 M. praemorsa were collected from Al-Bathan water body, Palestine, from November, 2010 to November, 2011. Cercariae in M. praemorsa were obtained by emerging and crushing methods. Results: Other three new different species of cercariae have been identified from this snail. These species were Xiphidiocercaria (Cercaria melanopsi palestinia IV), Microcercous (Cercaria melanopsi palestinia V) and Longifurcate cercaria (Cercaria melanopsi palestinia VI). The infection rate of M. praemorsa with these three different cercariae was (42.2%). Coinfection with Xiphidiocercariae and Longifurcate cercariae or Xiphidiocercariae and Microcercous cercariae has been noted and coinfection rate was 1.23% among the infected snails. The highest cercarial infection rate was in June (64.3%). No infected snails were found in September. It was also noted that infected s
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  • Thursday, November 24, 2011
  • Assessment of antifungal activity of herbal and conventional toothpastes against clinical isolates of Candida albicans
  • Published at:Asian Pacific Journal of Tropical Biomedicine (2012)
    Objective: To detect the anticandidal activity of nine toothpastes containing sodium fluoride, sodium monofluorophosphate and herbal extracts as an active ingredients  against 45 oral and non oral Candida albicans isolates.
    Methods: The antifungal activity of these toothpaste formulations was determined using  a standard agar well diffusion method. Statistical analysis was performed using a statistical package, SPSS windows version 15, by applying mean values using one-way ANOVA with post-hoc least square differences (LSD) method. A P value of <0.05 was considered significant.
    Results: All toothpastes studied in our experiments were effective in inhibiting the growth of all C. albicans isolates. The highest anticandidal  activity was obtained from toothpaste that containing both herbal extracts and sodium fluoride as an active ingredients, while the lowest activity was obtained from toothpaste containing sodium monofluorophosphate as an active ingredient. Antifung
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  • Thursday, November 10, 2011
  • Inhibitory Effect of Varthemia iphionoides Extract on the Contractility of Isolated Rabbit Ileum
  • Published at:Journal of Pharmacy Research 2011,4(12),4367-4368 by Yousef Salameh, Monther Abdel Fattah, Awni Abu-Hijleh, Ghaleb Adwan, Naser Jarrar and Kamel Adwan.
  • Varthemia iphionoides is indigenous to Palestine, where it is traditionally being used for treatment of gastrointestinal disorders. The aim of this paper was to
    provide pharmacological validation to this medicinal use. Water and ethanol extracts of Varthemia iphionoides were studied on isolated rabbit ileum for spasmolytic
    action. These extracts showed a reduction of the amplitude and the tone of spontaneous contraction in a concentration-dependent manner. Apart from that, water
    extract of Varthemia iphionoides drastically diminished the increase of the contraction of the ileum caused by acetylcholine (ACh) concentration of 5.5X10-6M.
    This indicates that Varthemia iphionoides extract probably acts at least through muscarinic receptors blockade
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  • Friday, May 20, 2011
  • Effect of ethanolic extract of Ecballium elaterium against Staphylococcus aureus and Candida albicans
  • Published at:Asian Pacific Journal of Tropical Biomedicine (2011)456-460
    Objective: To evaluate the antimicrobial activity of ethanolic extract of Ecballium elaterium (E. elaterium) fruits alone against Staphylococcus aureus (S. aureus) strains and Candida albicans (C. albicans) strains, or in combination with penicillin against Staphylococcus areus strains. Methods: Evaluation of the antimicrobial activity or synergy interaction was carried out using microdilution method. Results: The results showed that ethanolic extract of E. elaterium fruits has antimicrobial activity against methicillin resistant S. aureus (MRSA), methicillin sensitive S. aureus (MSSA) and C. albicans. This extract showed a significant decrease in minimum inhibitory concentration (MIC) of penicillin against both MRSA and MSSA strains. Fractional inhibitory concentration index (FIC) between penicillin and ethanolic extract E. elaterium fruits against these test strains were less than 0.5. Conclusions: This study suggests that ethanolic extract of E. elaterium fruits has antimicrobial activity aga
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  • Wednesday, March 16, 2011
  • Larval Stages of Digenetic Trematodes of Melanopsis praemorsa Snails from Freshwater Bodies in Palestine
  • Published at:Asian Pacific Journal of Tropical Biomedicine 2011; 200-204
    Objective: To detect the species of larval trematodes (cercariae) in Melanopsis praemorsa snails from 5 different fresh water bodies in Palestine. Methods: A total of Melanopsis praemorsa snails were collected from different fresh water bodies from October, 2008 to November, 2010. Cercariae in Melanopsis praemorsa were obtained by lighting and crushing methods. The behavior of cercariae was observed using a dissecting microscope. Results: Three different species of larval trematodes were identified from Melanopsis praemorsa snails collected only from Al-Bathan fresh water body, while snails from other water bodies were not infected. These species were a microcercous cercaria, xiphidiocercaria, and a brevifurcate lophocercous cercaria. These cercariae called Cercaria melanopsi  palestinia I, C. melanopsi palestinia II and C. melanopsi palestinia III  have not been described before from this snail in Palestine. The infection rate of Melanopsis praemorsa collected from
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Ghaleb Mohammad Adwan
Microbiology (Molecular Virology)
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