An-Najah National University

Rowa Jamal Al-Ramahi

 

 
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  • Wednesday, December 30, 2009
  • Drug Use and Dosing in Chronic Kidney Disease
  • Published at:Ann Acad Med Singapore 2009;38:1095-103
  • Yahaya Hassan, Rowa’J Al-Ramahi, Noorizan Abd Aziz, Rozina Ghazali

     

    One of the most important drug-related problems in patients with chronic kidney disease (CKD) is medication dosing errors. Many medications and their metabolites are eliminated through the kidney. Thus, adequate renal function is important to avoid toxicity. Patients with renal impairment often have alterations in their pharmacokinetic and pharmacodynamic parameters. The clearance of drugs eliminated primarily by renal fi ltration is decreased by renal disease. Therefore, special consideration should be taken when these drugs are prescribed to patients with impaired renal function. Despite the importance of dosage adjustment in patients with CKD, such adjustments are sometimes ignored. Physicians and pharmacists can work together to accomplish safe drug prescribing. This task can be complex and require a stepwise approach to ensure effectiveness, minimise further damage and prevent drug nephrotoxicity.

     

     http://www.annals.edu.sg/pdf/38VolNo12Dec2009/V38N12p1095.pdf

     
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  • Sapna said...
  • Nice post. Very Informative one. I got some more on <a href="http://en.wikipedia.org/wiki/Chronic_kidney_disease">chronic Kidney disease</a> from wiki. Anyway thanks for sharing it.
  • Thursday, December 31, 2009
  • Canadian pharmacies online said...
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  • Friday, April 30, 2010
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Rowa Jamal Abdulhafeez Al-Ramahi
Clinical Pharmacy
 
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