An-Najah National University

An-Najah Blogs


  • Sunday, September 30, 2007
  • Chewable tablets: Is this dosage form well evaluated by Palestinian health professionals?
  • Published at:Not Found
  • Abstract:
            Objective: To evaluate the scientific knowledge, assessment and attitudes of the three columns of health professionals in Palestine re the advantages of chewable tablets in comparison with other related dosage forms. Methods: Data was gathered from a questionnaire that was handed out to community pharmacists& Physicians. Pharmaceutical industry decision makers were enrolled in this study. Data was analyzed using spss statistical software program version 11.0. Results: Both pharmacists and doctors had very close opinions with regard to the superiority of chewable tablets over the corresponding liquid dosage forms, especially when issues of palatability, stability, dose precision, ease of administration, portability and safety are mentioned. Pharmacists and physicians were uncertain about the higher effectiveness of chewable tablets in comparison with other related dosage forms (syrups and suspensions) which contain the same active ingredients. Al
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  • Tuesday, May 25, 1999
  • effects of particle size and adding sequence of fine lactose on the deposition of salbutamol sulphate from a dry powder formulation.
  • Published at:international journal of pharmaceutics 182: 133-144
  • Ternary mixtures composed of coarse lactose (CL) (90.8 microm), salbutamol sulphate (SS) (5.8 microm) and either micronised lactose (ML) (5 microm) or intermediate sized lactose (IML) (15.9 microm) in a ratio of 66.5:1:1 w/w were prepared using different mixing sequences of the various components. In addition, a binary mixture composed of CL and SS (67.5:1 w/w) was also prepared as the control. The in vitro deposition of SS was measured using a twin stage impinger after aerosolisation at 60 and 90 l min-1 via a Rotahaler. The aerodynamic particle size distribution of both the aerosolised SS and lactose was further analysed using an Andersen cascade impactor at 60 l min-1. All ternary mixtures produced a significantly higher (analysis of variance, P<0.01) fine particle fraction (FPF) and fine particle dose (FPD) of SS than the control after aerosolisation at either 60 or 90 l min-1. Formulations containing the ML produced significantly (P<0.05) higher FPF and FPD of SS than those containing the IML at bo
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Abeer Omran Aref Abo-Ghosh
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