An-Najah National University

An-Najah Blogs


  • Thursday, January 1, 2009
  • Antibacterial Activity of Common Varthemia, Varthemia iphionoides Ethanol Extract Alone and in Combination with Cefotaxime
  • Published at:Advances in Biological Research 3 (5-6): 144-147, 2009
  • To assess the clinical utility of the crude ethanolic extract of the leaves of Varthemia iphionoides (Compositae), minimal inhibitory concentrations eJ\'v1Ies) were determined using agar dilution technique. Accordingly, The MICs of this plant extract ranged from 0.0313-1 mg/ml for three clinical Staphylacaccus aureus strains and ATCC strains of Bacillus subtilis and Staphylococcus epidermidis, whereas Escherichia coli studied in this report was fOlUld to exhibit higher 1v1Ie value (4 mg/ml). The effect of combinations of ethanolic extract of Varthemia iphionoides and cefotaxime was investigated by means of fractional inhibitory concentration (FIe) indices. Using the FIe indices, synergistic interactions were observed against B. subtilis (ATCC 6633) and S. aureus strains (FIC indices of 0.75-0.875); while combinations against E. cali and S. epidermidis (ATCC 25923) exhibited antagonistic interactions (FIC indices of 2.5 to 16.4). Synergy was confirmed at cefotaxime concentrations corresponding to 1/2 MIC and
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  • Tuesday, March 1, 2005
  • Nosocomial Infection Caused by Methicillin-Resistant Staphylococcus aureus in Palestine
  • Published at:Not Found
  • This report presents the prevalence of Palestinian isolates of methicillin-resistant Staphylococcus aureus (MRSA) in nosocomial infections and their antibiotic resistant pattern. A total of 321 clinical isolates of S. aureus were identified from different patients. The prevalence of methicillin resistance among S. aureus isolates was 8.7% (28 isolates). Resistance rates of MRSA to other antibiotics were as follows: 82.1% resistant to erythromycin, 67.9% to clindamycin, 64.3% to gentamicin, and 32.1% to ciprofloxacin. No co-trimoxazole- and vancomycin-resistant isolates were identified in this study. The proportion of methicillin resistance was highest among S. aureus isolates associated with upper respiratory specimens (42.8%); the proportion of methicillin resistance was 39.3% among skin ulcer isolates, 10.7% among urinary tract infection isolates, and lowest among isolates associated with blood and prostate discharge (3.6% each).
    Microbial Drug Resistance. March 1, 2005, 11(1): 75-77. d
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  • Thursday, January 1, 2004
  • Antibacterial Activities of Some Plant Extracts Utilized in Popular Medicine in Palestine
  • Published at:Turk J Biol 28 (2004) 99-102
  • The antibacterial activities of hot water, methanol and ethanol extracts of 5 plant extracts utilized in Palestine in popular medicine were studied. The dried extracts of Syzyium aromaticum (Myrtaceae) (seed), Cinnamomum cassia (Lauraceae) (cassia bark, Chinese cinnamon) (bark), Salvia officinalis (Lamiaceaea) (leaf), Thymus vulgaris (Lamiaceaea) (leaf) and Rosmarinus officinalis (Labiatae) (leaf) were tested in vitro against 4 bacterial species by disk diffusion and micro-dilution. The patterns of inhibition varied with the plant extract, the solvent used for extraction, and the organism tested. Methicillin-resistant Staphylococcus aureus (MRSA) and Bacillus subtilis ATCC 6633 were the most inhibited microorganisms. S. aromaticum extract was the most active against multidrug resistant Pseudomonas aeruginosa and enterohemorrhagic Escherichia coli O157 EHEC. The combinations of ethanolic extracts of S. officinalis with R. officinalis and of R. officinalis with T. vulgaris on bacterial species tested exhibited
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NAser Rusdi Mahmoud Jarrrar
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