An-Najah Blogs :: http://blogs.najah.edu/author/emp_2255 An-Najah Blogs :: en-us Sat, 23 Sep 2017 06:38:49 IDT Sat, 23 Sep 2017 06:38:49 IDT webmaster@najah.edu webmaster@najah.edu Antibacterial Activity of Common Varthemia, Varthemia iphionoides Ethanol Extract Alone and in Combination with Cefotaximehttp://blogs.najah.edu/staff/emp_2255/article/Antibacterial-Activity-of-Common-Varthemia-Varthemia-iphionoides-Ethanol-Extract-Alone-and-in-Combination-with-CefotaximePublished Articles To assess the clinical utility of the crude ethanolic extract of the leaves of Varthemia iphionoides Compositae minimal inhibitory concentrations eJ\v1Ies were determined using agar dilution technique Accordingly The MICs of this plant extract ranged from 00313-1 mgml for three clinical Staphylacaccus aureus strains and ATCC strains of Bacillus subtilis and Staphylococcus epidermidis whereas Escherichia coli studied in this report was fOlUld to exhibit higher 1v1Ie value 4 mgml The effect of combinations of ethanolic extract of Varthemia iphionoides and cefotaxime was investigated by means of fractional inhibitory concentration FIe indices Using the FIe indices synergistic interactions were observed against B subtilis ATCC 6633 and S aureus strains FIC indices of 075-0875; while combinations against E cali and S epidermidis ATCC 25923 exhibited antagonistic interactions FIC indices of 25 to 164 Synergy was confirmed at cefotaxime concentrations corresponding to 12 MIC and an ethanol extract concentrations corresponding to 141v1IC and lower Nosocomial Infection Caused by Methicillin-Resistant Staphylococcus aureus in Palestinehttp://blogs.najah.edu/staff/emp_2255/article/Nosocomial-Infection-Caused-by-Methicillin-Resistant-Staphylococcus-aureus-in-PalestinePublished ArticlesThis report presents the prevalence of Palestinian isolates of methicillin-resistant Staphylococcus aureus MRSA in nosocomial infections and their antibiotic resistant pattern A total of 321 clinical isolates of S aureus were identified from different patients The prevalence of methicillin resistance among S aureus isolates was 87 28 isolates Resistance rates of MRSA to other antibiotics were as follows: 821 resistant to erythromycin 679 to clindamycin 643 to gentamicin and 321 to ciprofloxacin No co-trimoxazole- and vancomycin-resistant isolates were identified in this study The proportion of methicillin resistance was highest among S aureus isolates associated with upper respiratory specimens 428; the proportion of methicillin resistance was 393 among skin ulcer isolates 107 among urinary tract infection isolates and lowest among isolates associated with blood and prostate discharge 36 each Microbial Drug Resistance March 1 2005 111: 75-77 doi:101089mdr20051175 Antibacterial Activities of Some Plant Extracts Utilized in Popular Medicine in Palestinehttp://blogs.najah.edu/staff/emp_2255/article/Antibacterial-Activities-of-Some-Plant-Extracts-Utilized-in-Popular-Medicine-in-PalestinePublished ArticlesThe antibacterial activities of hot water methanol and ethanol extracts of 5 plant extracts utilized in Palestine in popular medicine were studied The dried extracts of Syzyium aromaticum Myrtaceae seed Cinnamomum cassia Lauraceae cassia bark Chinese cinnamon bark Salvia officinalis Lamiaceaea leaf Thymus vulgaris Lamiaceaea leaf and Rosmarinus officinalis Labiatae leaf were tested in vitro against 4 bacterial species by disk diffusion and micro-dilution The patterns of inhibition varied with the plant extract the solvent used for extraction and the organism tested Methicillin-resistant Staphylococcus aureus MRSA and Bacillus subtilis ATCC 6633 were the most inhibited microorganisms S aromaticum extract was the most active against multidrug resistant Pseudomonas aeruginosa and enterohemorrhagic Escherichia coli O157 EHEC The combinations of ethanolic extracts of S officinalis with R officinalis and of R officinalis with T vulgaris on bacterial species tested exhibited a higher effect than that of any individual extract Results of this kind herald the interesting promise of designing a potentially active antibacterial synergized agent of plant origin