This study reports the association of noise pollution level with blood pressure (systolic and diastolic), heart rate and hearing threshold in school children. The schools were selected randomly as to present quiet [Seida village, 68.2-71.1 dB(A)], noisy [Nablus city, 76.5-79.4 dB(A)] and very noisy, [Tulkarem refugees camp, 82.4-85.9 dB(A)] localities. Strong positive correlation (Pearson Correlation Coefficient ) were found between noise pollution level and systolic and diastolic blood pressure, heart rate and hearing threshold at different frequencies. The mean systolic and diastolic blood pressure for the two sexes are correlated positively with the noise pollution level (R = 0.521 and 0.440, respectively). The hearing threshold levels of different frequencies correlated positively with the noise pollution level ( R = 0.114 to 0.267; where p c 0.05).