- Saturday, January 1, 1994
- α, β- Unsaturated Lactone-Nitrone Cycloadditions: a Route to the Synthesis of (±)–Tussilagin
- Published at:An-Najah J. Res. Vol. II, No. 8 (1994)
Reaction of nitrone (V with a, f1 -unsaturated lactone C.4) resulted in the isolation of a single adduct (7). The observed high regiochemical control has encouraged further explorations of natural product synthesis. A route to the synthesis of an interesting member of Pyrrolizidine- Alkaloid family; (±) -Tussilagin 90/ has been described.