- Friday, July 2, 2010
- Palladium(II)-catalyzed dicarboxymethylation of chiral allylic alcohols:
- Published at:Tetrahedron Letters 51 (2010) 3514–3517
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This manuscript describes the extension of Stille’s palladium-catalyzed olefin dicarbonylation reaction to chiral allylic alcohols with chirality transfer to afford the corresponding chiral alcohol functionalized with bis-carbomethoxy esters, containing three contiguous chiral centers, in good to excellent diastereoselectivities
(78–98%).
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