- Tuesday, January 20, 2009
- STROKE IN PATIENTS WITH AND WITHOUT DIABETES MELLITUS: CLINICAL CHARACTERISTICS, GENDER DIFFERENCES AND PREDICTORS OF IN-HOSPITAL MORTALITY
- Published at:Published at Journal of diabetes pp A224-225, 1(S1),2009. Publisher:Wiley InterScience.
College of Pharmacy, Clinical Pharmacy Department, Nablus, Palestinian Territory, Occupied
Published at Journal of diabetes pp A224-225, 1(S1),2009. Publisher:Wiley InterScience.
Accepted at 3rd international congress on prediabetes and metabolic syndrome ( Nice, France)
Objective: The objective of this study was to investigate and compare the clinical characteristics, gender differences and predictors of in-hospital mortality in stroke patients with and without diabetes mellitus (DM).
Methods: All patients admitted to Al-watani governmental hospital from September 2006 until September 2007 and diagnosed with acute stroke were included in the study. Demographic data, clinical characteristics, and predictors of in-hospital mortality in all patients were compared. Pearson chi-square test and student's t test were used in univariate analysis while multiple logistic regression was used to identify predictors of in-hospital mortality.
Results: 186 stroke patients met the inclusion criteria; their mean age was 69.09±10.9 years; 48.9% of them were males and 45.2% had a positive history of DM. Diabetic stroke patients were significantly younger (P= 0.009) and had higher proportion of ischemic heart disease (P=0.04) compared to non-diabetic stroke patients. In the total stroke patients, in-hospital mortality was 21%; 27.4% in diabetic and 15.7% in non-diabetic stroke patients. Univariate analysis of diabetic stroke patients based on gender showed that male patients significantly had more hemorrhagic strokes (P=0.04), recurrent strokes (P=0.003), number of risk factors (P=0.001), and in-hospital mortality (P=0.034) compared to females. Predictors of in-hospital mortality in diabetic stroke were stroke subtype (P=0.049) and number of post-stroke complications (P=0.002). However, no predictors of mortality in non-diabetic stroke patients were identified.
Conclusion: Diabetic stroke patients have different clinical characteristics, gender differences, and predictor's of mortality after acute stroke compared to non-diabetic stroke patients.