An-Najah National University



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  • Wednesday, March 1, 2006
  • 4-Hydroxy-2-quinolones. 92. Reaction of 1-R-4-chloro-3-ethoxycarbonyl-2-oxo-1,2-dihydroquinolines with anilines
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  • A preparative method is proposed and the synthesis of 4-arylamino-2-oxo-1,2-dihydroquinolines has been effected. An X-ray structural investigation of 4-(4-chlorophenylamino)-2-oxo-1-propyl-1,2-dihydroquinoline-3-carboxylic acid has been carried out enabling the ease of decarboxylating such compounds to be substantiated. Results are given of a study of the anti-inflammatory activity of the synthesized compounds.

    Chemistry of Heterocyclic Compounds, Volume 42, Number 3 / March, 2006

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Nidal Amin Ahmad Jaradat
Pharmaceutical chemistry and pharmacognosy
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