An-Najah National University

Publications of Waleed M. Sweileh,

Research Interests: 1.Clinical Renal Pharmacology and Therapeutics 2.Evidence Based Pharmacotherapy 3.Pharmacoepidemiology

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  • Friday, January 31, 2003
  • Pharmacotherapeutic Analysis and Prescription Pattern of ‎Antihypertensive Drugs Dispensed at Community Pharmacies in Palestine‎
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  • Pharmacotherapeutic Analysis and Prescription Pattern of

    Antihypertensive Drugs Dispensed at Community Pharmacies in Palestine

    Waleed Sweileh

    College of Pharmacy, An-Najah National University, Nablus, Palestine.

    E-mail: [email protected]

    Received: (30/12/2002), Accepted: (25/5/2003)



    The objective of this study is to explore the influence of current therapeutic

    recommendations on the prescribing trends of anti-hypertensive drugs in general

    medical practice in Palestine. Five hundred and seventy four anti-hypertensive

    prescriptions were analyzed. The percentage of mono-therapy prescriptions was 48.25%

    and that for combinational therapy prescriptions was 51.75%. Among the mono-therapy


    blockers were the most commonly prescribed, while diuretics were

    under-utilized. Inappropriate dose strength of atenolol was seen in mono-therapy

    prescriptions. Expensive and newer angiotensin converting enzyme inhibitor drugs

    (ACE-I) and calcium channel blocking drugs (CCB) were frequently seen in mono

    therapy prescriptions. Among the combinational therapy, the blockers / diuretics was

    most common. Irrational combinational therapy of -blockers / ACE-I was noticed. Use

    of modern and new CCB, ACE-I and angiotensin II type 1 receptor antagonists (AT1-

    RA) was seen in both mono therapy and combinational therapy. The overuse of

    nonprefered drugs and the under-use of prefered medications is indicative that education

    of JNC VI guidelines for physicians and health professionals in Palestine is needed.

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Waleed M. Sweileh, Professor of Clinical Pharmacology & Pharmacy:
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