http://blogs.najah.edu/author/emp_2421 An-Najah Blogs :: en-us Fri, 26 Apr 2024 20:21:02 IDT Fri, 26 Apr 2024 20:21:02 IDT [email protected] [email protected] http://blogs.najah.edu/staff/emp_2421/article/Prevalence-of-Reduced-Renal-Function-among-Diabetic-Hypertensive-PatientsPublished ArticlesInt J Clin Physio Pathophysio Pharmacol 11:41-472009Original ArticlePrevalence of Reduced Renal Function among Diabetic Hypertensive PatientsWaleed M Sweileh Ansam F Sawalha Saed H Zyoud Samah W Al-Jabil Nasr Y ShraimCollege of Pharmacy Clinical Pharmacy Graduate Program An-Najah National University Nablus Palestine; Poison Control and Drug Information Center PCDIC An-Najah National University Nablus PalestineReceived October 12 2008 accepted November 4 2008 and available online November 15 2008Abstract: Patients with diabetes mellitus and hypertension are at high risk of vascular complications particularly renal deterioration This study aimed to evaluate the prevalence and the risk factors of reduced renal function corresponding to chronic kidney disease CKD stages 3 5 among diabetic hypertensive patients This is a retrospective cohort study of diabetic hypertensive patients attending A-Watani governmental medical center from August 2006 until August 2007 Creatinine clearance CrCl was estimated using the CockcroftGault equation Those with CrCl 60 ml min corresponding to CDK stages 3 5 were considered to have reduced renal function The prevalence of reduced renal function was calculated and the risk factors associated with it were evaluated using multiple logistic regression The following were the results found in this study: a the prevalence of reduced renal function among the study patients was 355 distributed as follows: 635 had stage 3 CKD 217 had stage 4 and 13 had stage 5 CKD b Patients with reduced renal function were elder had higher number of chronic diseases and had longer duration of diabetes and hypertension than those with CrCl 60ml min c Men had a higher prevalence of reduced renal function than women d Significant predictors of reduced renal function were older age duration of diabetes and number of chronic diseases based on logistic regression analysis Early and continuous screening of renal function among diabetic hypertensive patients is required to implement preventable strategies of end stage renal disease ESRD Better control of blood pressure and diabetes mellitus are important IJCEM811001Key Words: Prevalence reduced renal function diabetic hypertension diabetes mellitus