An-Najah Blogs :: An-Najah Blogs :: en-us Fri, 30 Oct 2020 03:19:55 IST Fri, 30 Oct 2020 03:19:55 IST Antibacterial Activity of Common Varthemia, Varthemia iphionoides Ethanol Extract Alone and in Combination with Cefotaxime Articles To assess the clinical utility of the crude ethanolic extract of the leaves of Varthemia iphionoides Compositae minimal inhibitory concentrations eJ\v1Ies were determined using agar dilution technique Accordingly The MICs of this plant extract ranged from 00313-1 mgml for three clinical Staphylacaccus aureus strains and ATCC strains of Bacillus subtilis and Staphylococcus epidermidis whereas Escherichia coli studied in this report was fOlUld to exhibit higher 1v1Ie value 4 mgml The effect of combinations of ethanolic extract of Varthemia iphionoides and cefotaxime was investigated by means of fractional inhibitory concentration FIe indices Using the FIe indices synergistic interactions were observed against B subtilis ATCC 6633 and S aureus strains FIC indices of 075-0875; while combinations against E cali and S epidermidis ATCC 25923 exhibited antagonistic interactions FIC indices of 25 to 164 Synergy was confirmed at cefotaxime concentrations corresponding to 12 MIC and an ethanol extract concentrations corresponding to 141v1IC and lower